Châteauneuf-du-Pape is an AOC for wine made near the village of Châteauneuf-du-Pape in the Rhône wine region.

Most wines produced are red, with 13 different grape varieties allowed although Grenache Noir is the most common. Others are Syrah, Mourvèdre, Cinsaut, Terret Noir, Muscardin and Vaccarèse.

This is the major wine region of the Southern Rhône Valley. Vineyards are located around Châteauneuf-du-Pape and in the neighboring villages Bédarrides, Courthézon and Sorgues - between Avignon and Orange.